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These observations come from clinical and preclinical research and should not be read as guidance for human use

PMID: 30071442

Protein expression studies

36 Interestingly, commonly used cardioprotective agents, including statins and ACE inhibitors, appear to indirectly enhance mitophagy signaling, highlighting their broader mechanistic relevance

The enzyme adenylate-activated protein kinase (AMPK), which acts as a sensor of cellular energy levels, influences ferroptosis by facilitating the phosphorylation of acetyl coenzyme A carboxylase (ACC) and the production of polyunsaturated fatty acids (35)